What is the SINGLE biggest caster of doubt on God's Word? SPECIFICLLY, not generally as the depravity of man and his sin nature... Seems to me it would have to be the "theroy of evolution" and the "scientists" that seem "hell-bent" on "proving" other than creation as it casts doubt on much of His Word and from the beggining (Gen 1:1). What got me thinking about this is 2Th 2:11 And for this cause God shall send them strong delusion, that they should believe a lie: and that it speaks of "a" lie KJV or "the" lie LITV SINGULAR, not believe lies or lying, but a or the lie. Thoughts, comments.