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Real Gospel or Pseudo-Gospel

Discussion in '2004 Archive' started by Mike Gascoigne, Mar 26, 2004.

  1. UTEOTW

    UTEOTW New Member

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    Hi Mike!

    BTW, I too am a chemical engineer. Interesting profession, eh?

    Allow me to fill in the details, if I may.

    Humans are among a handful of animals in the world who lack the ability to make their own vitamin C and must instead get it from their diet. Included in that group are all primates. Now, here is the interesting part. Vitamin C is made from a process involving four different enzymes. In humans, one of these enzymes, GLO, has been deactivated by the deletion of a single nucleotide. As it turns out, primates also have the same enzymes deactivated and when we have looked at their genomes they have the exact same nucleotide missing as in humans (Ohta and Nishikimi BBA 1472:408, 1999). The problems in the other animals that cannot make vitamin C are different than in the humans and primates. This is generally considered to be a strong indication of common descent concerning humans and the other primates.
     
  2. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    UTEOTW,

    If this is intended as an argument against creation, it's knocking over a straw-man because in the beginning, humans and all animals were vegetarian. (Gen. 1:29-30).

    In that case, the subject should be studied as a scientific curiosity, rather than part of the creation/evolution debate. The thing that puzzles me is, why should a mutated gene propagate itself through an entire population if it has no advantage? It might even be a disadvantage in dry, arid areas where fruit and veg don't grow easily. How can we be sure that the omission of a nucleotide reduces a gene to useless junk? Is it really a mutation, and do we understand the language of DNA well enough to tell the difference between useful information and junk?

    Mike
     
  3. UTEOTW

    UTEOTW New Member

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    Mike

    I meant it more as an explanation for why he would include it on his list. I am not really trying to inject myself into this discussion, I have done that on enough related topics elsewhere on this board. But I did think I could shed some light.

    I was not meaning to indict creationism so much as support common descent. I realize to you that doing one is the same as the other. As someone who is a creationist but who also recognizes that the earth is old and who no longer denies common descent, I have a different take on it. Of course, this also makes me your target. ;)

    I do not see why if would matter if all animals were vegetarians. If it mattered in the manner you implied, it would seem that all animals would lack the ability to make vitamin C. You are correct that it seems strange that a damaging mutation would spread thoughout the population, but if the diet were already varied enough to compensate, then it becomes neutral and there is no reason for it not to spread either.

    I think it becomes clear that this is indeed a mutation if you look at the vitamin C machinery in whole. Animals make vitamin C through a series of four different enzymes. I think the starting material is a form of sugar, but I do not remember for sure. In humans, three of the four enzymes are correctly made. These are present but cannot be utilized properly because the remaining piece of machinery is damaged. I do not believe that these three enzymes have any other purpose. This fourth enzyme is defective. When we compare the gene for the defective enzyme with that of other animals, we find that there is a single mistake in the copy of the gene that humans have, a deletion of a single nucleotide from the gene. I do not know of any purpose this defective gene serves.

    Now, if this is not really a mutation, then what purpose do the three functioning genes and the one non-functional gene serve? If they were merely junk, they would not be so close to the working machinery of other animals. It is like finding a car with a flat tire. The car does not function properly but there was obviously some purpose for it originally.

    The part where the same mistake is shared by all primates is where common descent comes in. We have a copying error that is present in all members of a wide variety of species. The most simple and probable explanation is that they all inherited it from a common ancestor. Especially when the species that share the mutation can all be grouped into a single order while no species outside that order have the same mutation. The twin nested heirarchy.

    I hope not to make a debate out of this, so I'll leave it at this. I have other things with which I disagree but I choose not to get into that now. I just hope this sheds some light on my some would hold that humans not manufacturing their own vitamin C is a single piece of the evidence for common descent.

    Have a good weekend,

    UTEOTW
     
  4. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    UTEOTW,

    I found the following page that says humans, primates and guinea pigs are unable to manufacture their own vitamin C, because of this pseudo-gene, and the mutation must have occurred in a primitive mammal.

    http://www.str.com.br/English/Scientia/plagiarized.htm

    However, that doesn't explain why the pseudo-gene appears in the entire population of some species. A neutral mutation should be expected to distribute itself at random, so that some members of a species have it and others don't.

    A much better explanation is that there must have been a genetic bottleneck, such as Noah's Flood. If the mutation occurred before the Flood, it could be passed on to an entire population through a single pair that were in the ark. To resolve this, I suppose we have to find some pre-Flood guinea pigs, preserved in the arctic ice like the wooly mammoth, and see if any of them have the complete gene for making vitamin C.

    Mike
     
  5. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    More good news. The book is now available at a much wider range of outlets, including Amazon in the USA, Canada, UK, France, Germany and Japan.

    See my web page:

    http://www.annomundi.co.uk/book_orders.htm

    Mike
     
  6. UTEOTW

    UTEOTW New Member

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    The mutation seen in guinea pigs is different from that in primates although it affects the same gene.

    A bottleneck could certainly explain why an effectively neutral mutation is present in all members of a species. What your explanation lacks is a reason why it would be present in all the different species of a given order.

    The link was interesting, BTW.
     
  7. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    UTEOTW,

    Noah didn't go out searching for animals, to take them into the ark. Instead, the animals came to him (Gen. 7:15), apparently following an instinct that caused them to migrate towards the ark. It seems that God, in his wisdom, chose that only primates with the mutation would be saved in the ark, so that in the post-flood world they would all be dependent on fruit and veg.

    As for Noah and his wife, and his three sons and their wives, there was a lot of intermarriage within families in those days, so it's possible that all eight people on the ark had the same mutation. Alternatively, God might have given them the mutation to prevent them from becoming totally carniverous. They were allowed to eat meat after the Flood, but only under certain restricted conditions. (Gen. 9:2-5).

    Mike
     
  8. UTEOTW

    UTEOTW New Member

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    I disagree, but enough of this. It is getting off topic.

    Congratulations on getting published. Good luck.
     
  9. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    UTEOTW,

    I agree that we've probably exhausted this subject, but I don't think it's off topic. Instead it's a classic example of something I have briefly discussed in my book, that whenever someone tries to talk about historical and theological issues related to creation, they always get asked science questions. That's the reason why almost half the book is made up of scientific appendices.

    Mike
     
  10. UTEOTW

    UTEOTW New Member

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    Mike

    I thought it was getting off topic from the way you framed the subject at the beginning of the thread. But you bring up an important topic closer to the original when you say "whenever someone tries to talk about historical and theological issues related to creation, they always get asked science questions."

    If you will indulge me to try and answer why from my point of view. I do not believe that you can divorce the issue of Creation from what the evidence from Creation itself tells us about its history. They must go hand in hand. Let me try and show you what I mean and do not take it the wrong way.

    If you make the strongest case possible that the Bible and Christianity are completely incompatible with an old universe, yet you can do nothing to refute the evidence for an old universe, then where are you? We handle that problem two different ways within our on minds and within our own faith. You stick to your interpretation and deny the physical evidence while I instead opt for an interpretation that allows an old universe and accept the evidence from Creation. We can go along happy, disagreeing on this but agreeing on other things.

    But there is that third option out there that too many people come to. And that is that Christianity is invalid because at its core it is incompatible with what is perceived as the reality of the history of the universe. And IMHO, when the argument is put forth that the Bible is incompatible with an old earth without a very strong case for the earth actually being young, that is the end result. Some will lose their faith over it while others will never be reached for Christ over it.

    And, again in my opinion, all the young earth advocates I have come across end up in that last category. They can make a pretty good argument for why we should interpret the Bible as indicating a young earth. Though not yet good enough to convince me that is the only way. But I have yet to run across those that make a good, strong scientific case for a young earth. And believe me I have tried. I started YEC and it was the ineptitude of the YEC arguments themselves that led me away from YEC and to start looking at other evidence.

    So I feel the need to bring up the science for those reasons. A lot of it is that I think, as we all do, that I have staked out the correct position. Another part is that I have always enjoyed playing the devil's advocate. I really hope you are right. And by challenging what I see as very bad YEC arguments, maybe some good ones can be distilled out. Not yet, however.

    We used to have a nice forum just for this but it went away. The moderators have told us to use the Other Religions/Doctrines forum at the very bottom for such discussions. There is usually something going on down there if you would like to come join us. You might bring some civility to the proceedings. This is obviously something you are both interested and knowledgeable in. I would be curious what you had to say. For instance, you said you had an appendix on thermodynamics. The standard YEC misunderstanding of the 2LOT where it is confused with disorder in the general sense was the first big kick in the pants for me from the YECers to push me away. I could knew the way we stated the second law in thermo ("It is impossible by a cyclic process to convert the heat absorbed by a system completely into work.") was completely different from what they were saying it was. I would be curious the way someone who actually understands thermo goes about it. But that is a subject for a different thread.

    UTEOTW
     
  11. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    The Bible doesn't actually say that the universe is young. It says "To him that rideth upon the heavens of heavens, which were of old". (Psalm 68:33). In my Cosmology appendix, I've discussed some of the theories that try to reconcile a young earth with an old universe. I think the solution, if there is one, probably has something to do with the properties of space and time, and the expansion of the universe, although I need to develop the theme further when I get some feedback from readers. It's early days yet, and the book has just gone out.

    There are lots of young earth creationists who try to use the laws of thermodynamics, but often they don't understand them well enough. There are different ways of quoting the second law, but it always amounts to the same thing - the descent to disorder, as both energy and matter are distributed to their surroundings.

    It's correct to say that you can't get 100% conversion of heat into work, at least not in any practical engine, although this is not a statement of the second law. It's a consequence of all three laws. You can only get 100% efficiency if the engine runs infinitely slowly and energy is discarded at absolute zero of temperature. It's all explained in my appendix on thermodynamics.

    Sometimes YECs have the correct arguments, but they don't understand the arguments correctly. They pick things up from creationist magazines, not realising that it's just a simplified version intended for a wide readership. Instead of trying to explain it themselves, they should have given you a textbook on thermodynamics. It's a pity they gave you a "kick in the pants", as you put it, because it was totally unnecessary.

    Mike
     
  12. Mike Gascoigne

    Mike Gascoigne <img src=/mike.jpg>

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    I'm pleased to say that my new book, "Impossible Theology: The Christian Evolutionist Dilemma" is now into mainstream Christian distribution. It has been accepted by Spring Arbor, the major distributor to Christian bookshops all over the USA. It has also been entered into the Bookstore Manager Database, Christian Books & More, and my publisher name "Anno Mundi Books" has appeared in their vendor list:

    http://www.bsmgr.com/vendors/default.asp?go=specs/table07.htm

    This is an achievement, not just for myself, but also for Baptist Board because it was the discussion on an earlier version of this topic (now in the archives) that got me going on this book.

    Mike
     
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