A couple of things to mention. Distributed programming started with project "Seti@home" and was used to search through data from the big radio-telescope in Puerto Rico. Although I'm not sure what people here think about the SETI program, it was very interesting the way it worked and there were some people found by the billions of clock cycles used on outside computers. These "hits" will be reviewed by Berkeley (the college hosting the program), on leased time on Cray mainframes.
In my book, crunching numbers for finding diseases is a much BETTER use of computer time, but the SETI program did prove out that distributed computer is great.
There is ONE word of warning that I wish to make to those considering using it. It is NOT advised to be used on a LAPTOP. WHY?
Modern laptops have non-dynamic processors which can actually be stopped. When they are not in use, the clock cycles are either dropped to a lower level or turned off completely. These shut-downs or slow-downs may occur hundreds of times a minute, but it lowers the average number of clock cycles tremendously. In other words, the processor only runs during the times it needs to do something. For instance, a word processor may only turn on the processor when it has a key hit or does an auto-save--or is commanded to do something else. The rest of the time, the processor is essentially idle (except for housekeeping of windows).
The point is, distributed processing forces the computer to run during these slow periods--it can cause a processor in a laptop to overheat or run hotter than normal continuously. A proccessor running at 2 GHZ uses a LOT of power while it is processing. Therefore, you not only pull heavily from your power-supply or battery, but you may reduce the life of a portable's chip-set.
This is the ONLY negative to this. Otherwise it is perfectly safe and certainly will be helpful to the organizations crunching tons and tons of data. It is a unique form of donating to the prevention of disease.
Please do not take this as a negative--I highly recommend it. I just don't using your laptop.
.........Great program.